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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHB4
All Species:
14.24
Human Site:
S848
Identified Species:
34.81
UniProt:
P54760
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54760
NP_004435.3
987
108270
S848
P
P
P
D
C
P
T
S
L
H
Q
L
M
L
D
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
G888
P
P
P
G
C
P
P
G
L
H
L
L
M
L
D
Rhesus Macaque
Macaca mulatta
XP_001097522
1001
110812
A869
P
P
M
D
C
P
T
A
L
H
Q
L
M
L
D
Dog
Lupus familis
XP_546948
1000
109917
S861
P
P
P
D
C
P
T
S
L
H
Q
L
M
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P54761
987
108904
S848
P
P
P
D
C
P
T
S
L
H
Q
L
M
L
D
Rat
Rattus norvegicus
P09759
984
109865
A852
P
P
M
D
C
P
A
A
L
H
Q
L
M
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521846
981
107213
S841
P
P
P
E
C
P
T
S
L
H
Q
L
M
L
D
Chicken
Gallus gallus
Q07498
988
109560
A856
P
P
M
D
C
P
T
A
L
H
Q
L
M
L
D
Frog
Xenopus laevis
Q91735
974
108246
A842
P
P
M
D
C
P
S
A
L
H
Q
L
M
L
D
Zebra Danio
Brachydanio rerio
O13146
981
109636
Y846
I
K
A
V
D
E
G
Y
R
L
P
A
P
M
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.2
58.4
95.5
N.A.
92.7
56.7
N.A.
87.4
57.5
56
50.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
60.9
72.1
96.6
N.A.
95.6
71.8
N.A.
91.4
72.3
72.7
67.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
86.6
100
N.A.
100
80
N.A.
93.3
86.6
80
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
93.3
100
N.A.
100
86.6
N.A.
100
93.3
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
40
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
70
10
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
90
10
10
90
0
90
0
% L
% Met:
0
0
40
0
0
0
0
0
0
0
0
0
90
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
90
90
50
0
0
90
10
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
40
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _